Are Post-Trial Observational Studies Useful?

Are post-trial observational studies useful?

For more than two centuries, the measurement of urinary proteins has been a standard tool for nephrologists to diagnose kidney disease. Renal disease is characterized by changes in the glomerular filtration barrier leading to increased urinary excretion of proteins, the main protein of which is albumin. This was later called macroalbuminuria and appeared to be associated with an increased risk ...

Correct sampling in observational studies.

This article has no abstract.

Observational studies on glucocorticoids are harmful!

Correspondence to Professor Maarten Boers; [email protected] In this issue, Apostopoulos et al report yet another observational study on the association of glucocorticoid (GC) treatment with a bad outcome, in this case damage accrual in SLE. Unsurprisingly, the association is present, and ‘independent’ of potential confounders. Unsurprisingly, the authors argue for a causal relationship. So what is ne...

Observational studies: why are they so important?

[Do post-mortem brain studies provide useful information for psychiatry?].

a Departamento de Farmacología, Universidad del País Vasco/Euskal Herriko Unibertsitatea, UPV/EHU, Leioa, Bizkaia, Spain b Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Spain c Instituto de Investigación Biocruces, Baracaldo, Bizkaia, Spain d Departamento de Especialidades Médico-Quirúrgicas, Universidad del País Vasco/Euskal Herriko Unibertsitatea, UPV/EHU, Leioa, Bizkai...